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"Some authors have claimed that the endogenous creatinine chromogen clearance method may profitable be used in the measurement of glomerular filtration rate which is usually represented by inulin clearance method (Popper and Mandel, Popper Mandel and Mayer, Findley, Goudsmit, Hayman, Halsted and Seyler, Steinitz and Turkand). The obvious advantages of using the of the former are : it does not require continuous intravenous infusion, frequent withdrawal of blood, and elaborate analytical procedures. In the work presented here, whole blood creatinine concentration in 167 cases and endogenous blood creatinine clearance in 155 cases and both plasma creatinine concentration and endogenous plasma creatinine clearance in 41 cases, of the normal Korean subjects were determined. Also in a group of 13 cases 74 endogenous blood creatinine clearance tests were performed repeatedly during the period of two to seven days."
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